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Verification of insertion-deletion markers (InDels) and microsatellites (STRs) as subsidiary tools for inferring Slavic population ancestry

Data publikacji: 03.2023

Archiwum Medycyny Sądowej i Kryminologii, 2022, Vol. 72 (3), s. 120 - 137

https://doi.org/10.4467/16891716AMSIK.22.015.17393

Autorzy

,
Karolina Hołub
Katedra Medycyny Sądowej, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy, Uniwersytet Mikołaja Kopernika w Toruniu,
, Polska
Wszystkie publikacje autora →
,
Boris A. Malyarchuk
Institute of Biological Problems of the North, Far-East Branch of the Russian Academy of Sciences, Magadan, Russia
https://orcid.org/0000-0002-0304-0652 Orcid
Wszystkie publikacje autora →
,
Miroslava V. Derenko
Institute of Biological Problems of the North, Far-East Branch of the Russian Academy of Sciences, Magadan, Russia
https://orcid.org/0000-0002-1849-784X Orcid
Wszystkie publikacje autora →
,
Nataša Kovačević-Grujičić
Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, Belgrade, Serbia
https://orcid.org/0000-0002-3837-1283 Orcid
Wszystkie publikacje autora →
,
Milena Stevanović
Serbian Academy of Sciences and Arts, Belgrade, Serbia
Faculty of Biology, University of Belgrade, Belgrade, Serbia
Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, Belgrade, Serbia
https://orcid.org/0000-0003-4286-7334 Orcid
Wszystkie publikacje autora →
,
Danijela Drakulić
Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, Belgrade, Serbia
https://orcid.org/0000-0001-6790-6673 Orcid
Wszystkie publikacje autora →
,
Slobodan Davidović
Institute for Biological Research “Siniša Stanković”, National Institute of Republic of Serbia, University of Belgrade, Belgrade, Serbia
https://orcid.org/0000-0001-9317-6870 Orcid
Wszystkie publikacje autora →
Tomasz Grzybowski
Katedra Medycyny Sądowej, Zakład Genetyki Molekularnej i Sądowej, Wydział Lekarski, Collegium Medicum Uniwersytetu Mikołaja Kopernika
, Polska
https://orcid.org/0000-0001-6228-6460 Orcid
Wszystkie publikacje autora →

Tytuły

Verification of insertion-deletion markers (InDels) and microsatellites (STRs) as subsidiary tools for inferring Slavic population ancestry

Abstrakt

Genetic markers for the prediction of biogeographical ancestry have proved to be effective tools for law enforcement agencies for many years now. In this study, we attempted to assess the potential of insertion-deletion markers (InDel) and microsatellites (STRs) as subsidiary polymorphisms for inference of Slavic population ancestry. For that purpose, we genotyped Slavic-speaking populations samples from Belarus, the Czech Republic, Poland, Serbia, Ukraine and Russia in 46 InDels and 15 STRs by PCR and capillary electrophoresis and analyzed for between-population differentiation with the use of distance-based methods (FST, principal component analysis and multidimensional scaling). Additionally, we studied a sample from a Polish individual of well-documented genealogy whose biogeographic ancestry had previously been inferred by commercial genomic services using autosomal single nucleotide polymorphisms (SNPs), mitochondrial DNA and Y-SNP markers. For comparative purposes, we used genotype data collected in the “forInDel” browser and allele frequencies from previously published papers. The results obtained for InDels and STRs show that the Slavic populations constitute a genetically homogeneous group, with the exception of the Czechs differing clearly from the other tested populations. The analysis of the known Polish sample in the Snipper application proves the usefulness of the InDel markers on the continental level only. Conversely, microsatellites not only improve prediction, but are also informative if considered as an independent set of ancestry markers.

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Informacje

Informacje: Archiwum Medycyny Sądowej i Kryminologii, 2022, Vol. 72 (3), s. 120 - 137

Typ artykułu: Oryginalny artykuł naukowy

Tytuły:

Angielski:

Verification of insertion-deletion markers (InDels) and microsatellites (STRs) as subsidiary tools for inferring Slavic population ancestry

Polski:

Weryfikacja markerów insercyjno-delecyjnych (InDels) i mikrosatelitarnych (STR) jako narzędzi pomocniczych do wnioskowania o pochodzeniu populacji słowiańskiej

Autorzy

Katedra Medycyny Sądowej, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy, Uniwersytet Mikołaja Kopernika w Toruniu,
Polska

https://orcid.org/0000-0002-0304-0652

Boris A. Malyarchuk
Institute of Biological Problems of the North, Far-East Branch of the Russian Academy of Sciences, Magadan, Russia
https://orcid.org/0000-0002-0304-0652 Orcid
Wszystkie publikacje autora →

Institute of Biological Problems of the North, Far-East Branch of the Russian Academy of Sciences, Magadan, Russia

https://orcid.org/0000-0002-1849-784X

Miroslava V. Derenko
Institute of Biological Problems of the North, Far-East Branch of the Russian Academy of Sciences, Magadan, Russia
https://orcid.org/0000-0002-1849-784X Orcid
Wszystkie publikacje autora →

Institute of Biological Problems of the North, Far-East Branch of the Russian Academy of Sciences, Magadan, Russia

https://orcid.org/0000-0002-3837-1283

Nataša Kovačević-Grujičić
Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, Belgrade, Serbia
https://orcid.org/0000-0002-3837-1283 Orcid
Wszystkie publikacje autora →

Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, Belgrade, Serbia

https://orcid.org/0000-0003-4286-7334

Milena Stevanović
Serbian Academy of Sciences and Arts, Belgrade, Serbia
Faculty of Biology, University of Belgrade, Belgrade, Serbia
Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, Belgrade, Serbia
https://orcid.org/0000-0003-4286-7334 Orcid
Wszystkie publikacje autora →

Serbian Academy of Sciences and Arts, Belgrade, Serbia

Faculty of Biology, University of Belgrade, Belgrade, Serbia

Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, Belgrade, Serbia

https://orcid.org/0000-0001-6790-6673

Danijela Drakulić
Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, Belgrade, Serbia
https://orcid.org/0000-0001-6790-6673 Orcid
Wszystkie publikacje autora →

Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, Belgrade, Serbia

https://orcid.org/0000-0001-9317-6870

Slobodan Davidović
Institute for Biological Research “Siniša Stanković”, National Institute of Republic of Serbia, University of Belgrade, Belgrade, Serbia
https://orcid.org/0000-0001-9317-6870 Orcid
Wszystkie publikacje autora →

Institute for Biological Research “Siniša Stanković”, National Institute of Republic of Serbia, University of Belgrade, Belgrade, Serbia

https://orcid.org/0000-0001-6228-6460

Tomasz Grzybowski
Katedra Medycyny Sądowej, Zakład Genetyki Molekularnej i Sądowej, Wydział Lekarski, Collegium Medicum Uniwersytetu Mikołaja Kopernika
, Polska
https://orcid.org/0000-0001-6228-6460 Orcid
Wszystkie publikacje autora →

Katedra Medycyny Sądowej, Zakład Genetyki Molekularnej i Sądowej, Wydział Lekarski, Collegium Medicum Uniwersytetu Mikołaja Kopernika
Polska

Publikacja: 03.2023

Otrzymano: 31.12.2022

Zaakceptowano: 07.02.2023

Status artykułu: Otwarte __T_UNLOCK

Licencja: CC-BY-NC-SA  ikona licencji

Udział procentowy autorów:

Karolina Hołub (Autor) - 12.5%
Boris A. Malyarchuk (Autor) - 12.5%
Miroslava V. Derenko (Autor) - 12.5%
Nataša Kovačević-Grujičić (Autor) - 12.5%
Milena Stevanović (Autor) - 12.5%
Danijela Drakulić (Autor) - 12.5%
Slobodan Davidović (Autor) - 12.5%
Tomasz Grzybowski (Autor) - 12.5%

Korekty artykułu:

-

Języki publikacji:

Angielski

Sugerowane cytowania: Nature

Hołub, K, Malyarchuk, B, Derenko, M, Kovačević-Grujičić, N, Stevanović, M, Drakulić, D, Davidović, S, Grzybowski, T. Weryfikacja markerów insercyjno-delecyjnych (InDels) i mikrosatelitarnych (STR) jako narzędzi pomocniczych do wnioskowania o pochodzeniu populacji słowiańskiej. Archiwum Medycyny Sądowej i Kryminologii 2022, 120-137 (2023)