The article presents the changes in the population size of the Russian Federation in the vast area of Siberia and the Russian Far East. On the territory of more than 13 mln km2 (within the Ural, Siberian and Far East Federal District) population in this period (in the years 1989–2010) declined from 41.54 million in 1989 to 39.13 million in 2002 and 37.63 million in 2010, i.e. during 21 years decreased by 3.91 million people, i.e. about 9.41%! (the population of Siberian Federal District has decreased by 1.81 million and the Far East District by 1.65 million people). In the same period the population of the Russian Federation decreased by 4.16 million people, of which 93.99% were just the people of Siberia and the Far East.

Statistical data are based on the results of censuses conducted in 1989, the last time in the Soviet Union, and in the years 2002 and 2010 in the Russian Federation.