Postmortem diagnosis of arterial atherosclerosis in autopsy, postmortem computed tomography and histopathological examinations in medico-legal aspect = Pośmiertna diagnostyka miażdżycy naczyń tętniczych w badaniach sekcyjnych, w pośmiertnym badaniu tomografią komputerową oraz w badaniach histopatologicznych w aspekcie medyczno-sądowym
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RIS BIB ENDNOTEData publikacji: 04.06.2024
Archiwum Medycyny Sądowej i Kryminologii, 2024, Vol. 74 (1), s. 50 - 63
https://doi.org/10.4467/16891716AMSIK.24.004.19649Autorzy
Postmortem diagnosis of arterial atherosclerosis in autopsy, postmortem computed tomography and histopathological examinations in medico-legal aspect
The aim of this study is to provide a retrospective assessment of the possibility of determining the severity of atherosclerosis based on postmortem computed tomography (PMCT), autopsy protocols and histopathological examination results. In the first stage of the study, 200 cases were evaluated of persons over 40 years of age in whom postmortem computed tomography and autopsy were performed. In the second stage, the cases were divided into a study group (cardiovascular deaths) and a control group, as well as divided by age and, in addition to autopsy protocols and PMCT results, histopathological findings were evaluated.
The results of stage I demonstrated that the best detection of atherosclerosis was in the advanced stage with a predominance of detection in PMCT. Atherosclerosis detection in autopsy was highest in the coronary arteries, aorta and cerebral arteries; while in PMCT it remained equal in all evaluated locations. Autopsy showed higher detection of advanced atherosclerotic lesions in the coronary arteries and aorta compared to PMCT. The results of stage II of the study revealed that attaching the results of the general histopathological examination to the retrospective evaluation does not provide an opportunity to increase the accuracy of the evaluation of atherosclerotic lesions. The results obtained indicate the need for prospective studies.
Conclusions: autopsy allows macroscopic evaluation of a very broad spectrum of atherosclerotic lesions, but often without precise determination of their nature, and with limited localization; PMCT allows accurate and reproducible evaluation of calcified atherosclerotic lesions in large and medium-sized vessels, but is unsuitable for the evaluation of non-calcified lesions and small vessels; targeted histopathological examinations allow very accurate, but local assessment of atherosclerotic lesions.
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Informacje: Archiwum Medycyny Sądowej i Kryminologii, 2024, Vol. 74 (1), s. 50 - 63
Typ artykułu: Oryginalny artykuł naukowy
Tytuły:
Katedra Medycyny Sądowej Collegium Medicum Uniwersytetu Jagiellońskiego w Krakowie
Polska
Dietrich-Bonhoeffer Klinikum Neubrandenburg
Niemcy
Katedra Medycyny Sądowej Collegium Medicum Uniwersytetu Jagiellońskiego w Krakowie
Polska
Katedra Medycyny Sądowej Collegium Medicum Uniwersytetu Jagiellońskiego w Krakowie
Polska
Katedra Medycyny Sądowej Collegium Medicum Uniwersytetu Jagiellońskiego w Krakowie
Polska
Publikacja: 04.06.2024
Otrzymano: 23.02.2024
Zaakceptowano: 16.04.2024
Status artykułu: Otwarte
Licencja: CC-BY-NC-SA
Udział procentowy autorów:
Korekty artykułu:
-Języki publikacji:
Angielski, PolskiLiczba wyświetleń: 207
Liczba pobrań: 102