TY - JOUR TI - Feature Selection and Classification Pairwise Combinations for High-dimensional Tumour Biomedical Datasets AU - Wosiak, Agnieszka AU - Dziomdziora, Agata TI - Feature Selection and Classification Pairwise Combinations for High-dimensional Tumour Biomedical Datasets AB - This paper concerns classification of high-dimensional yet small sample size biomedical data and feature selection aimed at reducing dimensionality of the microarray data. The research presents a comparison of pairwise combinations of six classification strategies, including decision trees, logistic model trees, Bayes network, Na¨ıve Bayes, k-nearest neighbours and sequential minimal optimization algorithm for training support vector machines, as well as seven attribute selection methods: Correlation-based Feature Selection, chi-squared, information gain, gain ratio, symmetrical uncertainty, ReliefF and SVM-RFE (Support Vector Machine-Recursive Feature Elimination). In this paper, SVMRFE feature selection technique combined with SMO classifier has demonstrated its potential ability to accurately and efficiently classify both binary and multiclass high-dimensional sets of tumour specimens. VL - 2015 IS - Volume 24 PY - 2016 SN - 1732-3916 C1 - 2083-8476 SP - 53 EP - 62 DO - 10.4467/20838476SI.15.005.3027 UR - https://ejournals.eu/en/journal/schedae-informaticae/article/feature-selection-and-classification-pairwise-combinations-for-high-dimensional-tumour-biomedical-datasets KW - dictionary learning KW - sparse representation KW - anomaly detection