TY - JOUR
TI - Biomechanical aspects of atherosclerosis
AU - Wasilewski, Jarosław
AU - Mirota, Kryspin
TI - Biomechanical aspects of atherosclerosis
AB - 
	Pathogenesis of atherosclerosis is a complex multifactorial process of vascular wall injury. It is widely accepted that the local hemodynamic factors, in particular, disturbed flow and low/ oscillatory shear stress leads to the plaque development. We present a consistent concept of atherosclerosis aetiology, taking into consideration the four main components contributing in the atheroma formation: geometric, hemodynamic, hemorheological, and mechanical risk factors. Exemplary illustrative flow simulation results for formulated concept have been presented. It assumes the pulsatile non-Newtonian fluid flow and uses realistic coronary artery geometry based on medical imaging and segmentation.
VL - 2013
IS - Chemia Zeszyt 1-Ch (1) 2013
PY - 2014
SN - 0011-4561
C1 - 2353-737X
SP - 89
EP - 98
DO - 10.4467/2353737XCT.14.042.2625
UR - https://ejournals.eu/czasopismo/czasopismo-techniczne/artykul/biomechanical-aspects-of-atherosclerosis
KW - atherosclerosis pathogenesis
KW - shear stress
KW - computational fluid dynamics